Being overweight is a definite aggravating factor for reflux by increasing intrabdominal pressure.
Patients with long standing diabetes may develop decreased gastric emptying due to nerve injury to the stomach. This can also occur after certain stomach surgeries. Ulcers or cancers that block the stomach from emptying can cause reflux. Certain medications can contribute to reflux. Scleroderma is a rheumatological problem that can lead to reflux secondary to poor esophageal emptying and a decreased lower esophageal sphincter pressure.
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Important: This information should not be used as a substitute for the medical care and advice of your physician.