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30% of celiac disease patients may develop a malignancy, therefore adhering to a gluten-free diet is critical for preventive purposes. |
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In children, stunted growth and an inability to gain weight are important clues to diagnosis. More unusual features of celiac disease appear to be related to an altered immune system. These include a skin condition called dermatitis herpetiformis, insulin-dependent diabetes, thyroid disease and underactivity of the adrenal glands. |
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Today, many patients have minor symptoms or none at all and the disease is only discovered after routine testing reveals anemia (low red blood cell count) or osteoporosis. In hindsight, many patients will realize that they have had minor symptoms that they ignored. |
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It is not known why certain people have this allergy to gluten but studies suggest that there are both genetic and environmental components. Traditionally, this disease was found to be more common in patients with northern European backgrounds, such as Ireland and Scotland. However, more recent reports suggest that celiac disease occurs in other racial and ethnic groups. |